What are the health effects of pod-based vaping? | Life

The health effects of e-cigarettes can be different depending on the flavor used. — Stock Photo Shutterstock

PARIS, April 21 — With their sweet flavors and colorful packaging, certain types of electronic cigarettes appeal to young consumers.

However, according to a recent US study, daily use of pod-based vapes can alter the inflammatory state of the brain, heart, and colon.

Some 12 million consumers in the United States use electronic cigarettes, according to researchers at the University of California, San Diego, with the highest rates among 18-24 year olds.

With sweet flavors, colorful packaging and easy-to-use formats, certain types of e-cigarettes may particularly appeal to young users.

Researchers have studied the effects of e-cigarettes on health, focusing in particular on pod e-cigarettes manufactured by the JUUL LABS brand, one of the most popular in the field.

To conduct their study, the specialists exposed mice to flavored JUUL aerosols three times a day for three months. The particularly popular flavors of mint and mango were chosen for the experiment.

In their study published in the journal e-lifethe specialists state that their findings “suggest that daily e-cigarette use may induce neuroinflammation, which may contribute to behavioral changes and mood disorders.”

According to specialists, the area of ​​the brain particularly affected is the nucleus accumbens, a brain region essential for motivation and the processing of rewards.

“Many JUUL users are teenagers or young adults whose brains are still developing, so it’s pretty terrifying to learn what may be going on in their brain considering how it could affect their mental health and their behavior,” said Laura Crotty Alexander, lead author of the study. , MD, associate professor of medicine at UC San Diego School of Medicine.

The researchers also noted an increase in the expression of inflammatory genes in the colon, “which could increase the risk of gastrointestinal disease”, they explain. In contrast, the heart was found to have reduced levels of inflammatory markers. The authors suggest this could make heart tissue more vulnerable to infection.

Distinct effects of different flavors

The inflammatory response of the organs studied also turned out to be different depending on the aromas tested. For example, “the hearts of mice that inhaled mint aerosols were significantly more sensitive to the effects of bacterial pneumonia than those that inhaled mango aerosols,” the researchers explain.

“If someone who frequently uses menthol-flavored JUUL e-cigarettes were infected with Covid-19, their body may react differently to the infection,” warns Laura Crotty Alexander. “This shows us that aromatic chemicals themselves also cause pathological changes,” concludes the specialist. — Studio ETX

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