Beneficial effects of salt substitutes on BP are consistent – Consumer Health News
WEDNESDAY, Aug. 10, 2022 (HealthDay News) — The beneficial effects of salt substitutes on blood pressure appear to be consistent across regions and populations, according to a study published online on 9 august in Heart.
Xuejun Yin, of the George Institute for Global Health at the University of New South Wales in Newtown, Australia, and colleagues conducted a systematic review to examine the effects of salt substitutes on outcomes to understand the likely generalizability of the findings of the Salt Substitute and Stroke Study, which reported the blood pressure-mediated benefits of a potassium-enriched salt substitute. Data were included from 21 trials with 31,949 participants; 19 reported effects on blood pressure and five reported effects on clinical outcomes.
The researchers found that the overall reduction in systolic and diastolic blood pressure was -4.61 and -1.61 mm Hg, respectively. Consistent reductions in blood pressure were observed across geographic regions and population subgroups defined by age, gender, history of hypertension, body mass index, baseline blood pressure, and blood pressure. 24-hour baseline urinary sodium and potassium. Each 10% lower proportion of sodium chloride in the salt substitute was associated with a greater reduction of -1.53 and -0.95 mm Hg in systolic and diastolic blood pressure, respectively. Clear protective effects were observed for salt substitute on total mortality, cardiovascular mortality, and cardiovascular events (hazard ratios, 0.89, 0.87, and 0.89, respectively).
“These findings are unlikely to reflect the game of chance and support the adoption of salt substitutes in clinical practice and public health policy as a strategy to reduce dietary sodium intake, increase dietary intake potassium, lower blood pressure and prevent major cardiovascular events,” the authors write.