American Heart Association – InsuranceNewsNet

2022 NOV 11 (NewsRx) — By a News Reporter – Staff News Editor at Daily Insurance NewsDALLAS– Using pod-based e-cigarettes can lead to exposure to volatile organic compounds (VOCs) that can negatively affect cardiovascular health in the same way as smoking traditional cigarettes, according to preliminary research to be presented at the American Heart Association’s 2022 Scientific Sessions. The meeting, held in person at Chicago and virtually, November 5-7, 2022is a leading global exchange of the latest scientific advances, research and evidence-based clinical practice updates in the field of cardiovascular sciences.

VOCs are a broad group of gases found in many common items, such as cleaning products, paint, cigarettes, vehicle exhaust, pesticides, and other substances. According to United States Environmental Protection Agencythe ability of volatile organic chemicals to cause health effects varies widely from being highly toxic to having no known health effects.

“Pod-based e-cigarettes are commonly marketed to youth and young adults, as well as people who are trying to quit or cut down on regular cigarette smoking,” said the study’s lead author. Sana MajidMD, MS, postdoctoral fellow at Boston University School of Medicine. “However, the long-term health effects of using these new tobacco products are currently unknown, which is why we conducted this study.”

As part of the American Heart Association Tobacco Center for Regulatory Science (TCORS), Majid and colleagues assessed the impact of pod e-cigarettes on heart health. This observational study, in which participants visited the study center once, compared vascular effects related to VOC exposure in pod e-cigarette users, fuel cigarette users, and people who declared not to use tobacco or nicotine.

The study included 106 young adults, aged 18 to 45, with no cardiovascular disease or risk factors (no diagnosis or increased risk of hypertension, type 2 diabetes or dyslipidemia (high cholesterol)). Participants were recruited between 2019 and 2021 at Boston University School of Medicine and at the University of Louisville in Louisville, Kentucky. Participants were primarily local residents, as well as students and faculty members. Participants identified as 49% male and 51% female; 35% of pod e-cigarette users were female, 33% of fuel cigarette users were female, and 81% of non-smokers were female.

About 45% (48) of participants used pod e-cigarettes; 20% (21) smoked combustible cigarettes; and 35% (37) reported not using tobacco in any form. At the time of the study, 37% of pod e-cigarette users said they had never smoked traditional cigarettes; 64% used e-cigarettes exclusively; and 36% used both e-cigarettes and combustible cigarettes.

The participants’ vascular function (functioning of the arteries and veins that move blood throughout the body) and blood pressure were measured before and after using their favorite tobacco product for 10 minutes. Measurements were taken in one day, during one clinic visit for each participant. Vascular function was measured by examining flow-mediated dilation of the brachial artery – the widening of the artery in the arm in response to increased blood flow – both before and 30 minutes after the participants used their preferred tobacco product, with a single measurement taken at both time points. Blood pressure and heart rate were measured 10 minutes after the participants used their preferred tobacco product, with the researchers recording the average of three readings before and after using the product. Urinary VOC levels were measured at baseline and one hour after using e-cigarettes or traditional cigarettes.

The results revealed that young adults who use pod e-cigarettes experienced changes in blood vessel health similar to traditional cigarette smokers:

“Our results demonstrate that pod-based e-cigarette use has long- and short-term effects on the vascular system in healthy young adults, including those who have only smoked e-cigarettes. and have never smoked combustible cigarettes. These results indicate that e-cigarettes release chemicals that are toxic to blood vessels, and the use of pod e-cigarettes may be associated with harm,” said Majid said Long-term effects included participants’ baseline readings for blood pressure and heart rate and short-term effects included those readings after participants used e-cigarettes or combustible cigarettes.

The use of pod e-cigarettes has increased among youth and young adults in recent years. “Youth and young adults should avoid using tobacco products, including pod e-cigarettes, as they can harm blood vessel health. Establishing regulations that make it harder for young people to start using e-cigarettes is an important part of achieving a tobacco-free future,” she continued. “We also need better approaches to help people stop using all tobacco products and expand support and access to cessation programs and medications.

Study limitations included participants using their own tobacco product, which made it difficult to isolate the effects of each of the products’ individual components, such as nicotine levels or flavors, as well as differences in vascular function. in each participant that may be associated with the use of specific types or brands of tobacco products. Additionally, most participants used mint-flavored pods, and larger studies may be needed to capture the differences associated with different flavor types.

The co-authors are Jessica L. FettermanPh.D.; Robert M. WeisbrodMY; Andrew C. StokesPh.D.; Michael J. BlahaMD, MPH; Sanjay SrivastavaPh.D., FAHA; Rose M.RobertsonMD, FAHA; Aruni BhatnagarPh.D., FAHA; Rachel J. Keith, Ph.D., APRN, ANP-C.; and Naomi M. Hamburg, MD, MS, FAHA. Author disclosures are listed in the abstract.

The study was funded by the American Heart Association Tobacco Regulatory Research Center with grants from the WE food and Medication Administration Center for Tobacco Products through the National Heart, Lung and blood institutea division of National Institutes of Health. Through this Center, the American Heart Association works closely with researchers at institutions across the country to pursue research that adds to existing knowledge about the health effects of smoking and nicotine-related products, including e-cigarettes, results that can help inform public health and tobacco product regulation.

Statements and conclusions of studies that are presented at American Heart Association scientific meetings are solely those of the study authors and do not necessarily reflect the policy or position of the Association. The Association makes no representations or warranties as to their accuracy or reliability. Abstracts presented at the Association’s scientific meetings are not peer-reviewed, but rather by independent review committees and are considered based on the potential to add to the diversity of scientific issues and viewpoints discussed. during a meeting. Results are considered preliminary until published as a full manuscript in a peer-reviewed scientific journal.

The Association receives funds primarily from individuals; foundations and corporations (including pharmaceutical companies, device manufacturers, and other businesses) also donate and fund Association-specific programs and events. The Association has strict policies to prevent these relationships from influencing scholarly content. Revenues from pharmaceutical and biotechnology companies, device manufacturers, and health insurance providers as well as the Association’s aggregate financial information are available here.

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The American Heart Association’s 2022 Scientific Sessions are a premier global exchange of the latest scientific advances, research, and evidence-based clinical practice updates in cardiovascular science. The 3-day meeting will feature over 500 sessions focused on groundbreaking updates in basic, clinical, and population science cardiovascular sciences, Saturday through Monday, November 5-7, 2022. Thousands of leading physicians, scientists, cardiologists, advanced practice nurses and allied health professionals from around the world will gather virtually to participate in basic, clinical and population science presentations, discussions and programs that can shape the future of cardiovascular science and medicine, including prevention and quality improvement. During the three-day meeting, attendees receive exclusive access to more than 4,000 original research presentations and can earn continuing medical education (CME), continuing education (CE), or certification maintenance credits ( MOC) for training sessions. Take part in the 2022 scientific sessions on social networks via #AHA22.
The keywords in this news article include: American Heart AssociationBlood pressure, Blood vessels, Cardio system, Cardiology, Cardiovascular, Cardiovascular diseases and conditions, Cardiovascular researchCardiovascular system, Chemicals, Health and medicine, Heart rate, Hemodynamics, Hypertension, Medical devices, Risk and prevention, Smoking.

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