MONDAY, Nov. 7, 2022 (HealthDay News) — Significant negative effects on cardiovascular function are seen in people who vape, according to two studies based on the Cardiac and Lung E-cig Smoking (CLUES) cross-sectional study and presented at Scientific Sessions 2022 of the American Heart Association, held November 5-7 in Chicago.
Matthew C. Tattersall, DO, of the University of Wisconsin-Madison, and colleagues examined differences in cardiovascular and autonomic function responses to the use of electronic nicotine delivery devices (ENDS) by chronic users of ENDS (vapers), use of combustible cigarettes (smokers), and no product use among non-smokers/non-vapers controls (164, 117, and 114 participants, respectively). Systolic and diastolic blood pressure (BP), heart rate, brachial artery diameter, and time-domain heart rate variability were examined before and 15 minutes after a test use of the product. Researchers found that vapers had greater increases in systolic blood pressure, diastolic blood pressure, and heart rate and had greater reductions in brachial artery diameter compared to controls, as well as reductions larger successive rms differences in successive normal intervals and percentage of adjacent normal intervals >50 ms than controls; the values were similar to those of smokers.
Christina M. Hughey, MD, of the University of Wisconsin-Madison, and colleagues examined whether treadmill stress test results differed for vapers, smokers, and controls in the CLUES study (164, 117 and 114 participants, respectively). Participants completed a symptom-limited Balke treadmill stress test protocol an average of 91.3 minutes after vaping, smoking, or resting. Researchers found that compared to controls, vapers performed worse on all four exercise parameters: peak metabolic equivalents, peak rate-pressure product, heart rate reserve, and rate recovery. cardiac in 60 seconds; values for vapers were intermediate compared to smokers.
“Our results from the CLUES study raise concerns about the potential harms of chronic use of electronic nicotine delivery systems, particularly for cardiovascular disease,” a co-author from both studies said in a statement.
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